By Errol C Friedberg
With a Foreword through Sydney Brenner (Nobel laureate in body structure or drugs, 2002)
This biography info the lifetime of Paul Berg (Emeritus Professor at Stanford University), tracing Berg's existence from start, in 1926, to the current, with designated emphasis on his huge, immense medical contributions, together with being the 1st to boost know-how that ended in gene cloning technology. In 1980, Berg obtained a Nobel Prize in chemistry for this work.
as well as his contributions within the learn laboratory, Berg orchestrated and oversaw a historical assembly at Asilomar, California that situated on a threatening controversy surrounding the conception by means of a number of the damaging capability of recombinant DNA expertise. This assembly did a lot to prevent this controversy and to install position the legislation of recombinant DNA paintings, therefore placing fears to rest.
The recombinant DNA controversy was once a ancient final result of the invention of gene cloning. particularly, it represented a paramount instance of clinical foresight and due diligence by way of the medical neighborhood, instead of by way of regulatory entities within the usa and plenty of different international locations. the last word recognition of gene/DNA cloning resulted in a brand new period of contemporary biology that flourishes to the present.
This ebook is aimed basically at scientists and people in education. The publication strives to easily offer details for the final reader, yet isn't really particularly adapted for a normal studying audience.
whereas many books disguise the recombinant DNA controversy, none have satisfactorily addressed this historical interval and are frequently contradictory in regards to the many who is, where's, and why's concerned. also, the nice majority of those have been written through non-scientists. This biography of Paul Berg presents entry to varied archived letters and files at Stanford college now not formerly addressed, and to the chronology of occasions as recalled and documented through him, in addition to different key personalities, lots of whom have been interviewed.
Readership: Researchers, graduate scholars, undergraduates in lifestyles sciences, medication and chemistry and lay public.
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Additional info for A Biography of Paul Berg : The Recombinant DNA Controversy Revisited
Notwithstanding his protracted interest in science, especially biology, as the college years approached Berg’s thoughts turned to chemical engineering as a career choice. “I don’t remember exactly what motivated my interest in chemical engineering,” he reflected. indd 21 23-05-2014 09:57:48 b1674 The Recombinant DNA Controversy Revisited 22 b1674_Ch-03 A Biography of Paul Berg An unanticipated logistical nightmare brought an abrupt halt to the City College of New York experience after a mere three days, when Berg (belatedly) realized that commuting back and forth between home at the southern tip of Brooklyn and City College in upper Manhattan consumed about five hours!
Indd 11 23-05-2014 09:55:41 b1674 The Recombinant DNA Controversy Revisited 12 b1674_Ch-01 A Biography of Paul Berg Berg (and many other students who entered the halls of Abraham Lincoln High) particularly revered a woman staff member named Sophie Wolfe. 18 Wolfe was not a formally trained teacher. Her official responsibility was to supervise the school supply room that stocked various materials (a variety of models, chemical equipment and microscopes) regularly used during science lectures. She also orchestrated and managed the so-called Biology Club, an informal group of student stalwarts that met most days after classes to pursue their interests in science, which Berg enthusiastically joined on many afternoons.
Indd 10 23-05-2014 09:55:41 b1674 The Recombinant DNA Controversy Revisited b1674_Ch-01 Growing up in Brooklyn 11 with living things was first aroused from reading books), Berg’s curiosity was primarily piqued by his nurturing educational environment — and by spotting the occasional dead animal in a sufficient state of preservation to take home to dissect! 14 “At that early stage these interests sometimes translated to an ambition to become a doctor. ” “I can’t remember ever seeing either of them reading books,” he stated.